Group B Streptococcus: working towards a global solution for a global problem (123917)
Reducing death at and around birth is critical worldwide. Infection is an important cause of this mortality, and group B streptococcus (GBS, Streptococcus agalactiae) is a leading cause, resulting in around 130,000 perinatal and infant deaths annually. Interventions to reduce GBS through screening and intrapartum-antibiotic prophylaxis have been applied in high income countries but are unlikely to reduce stillbirth -associated GBS disease and/or late onset neonatal GBS disease. An effective GBS vaccine given in pregnancy could reduce this burden, but has, does, and will, require collaboration and innovation from partners worldwide.