Shiranee Sriskandan is Professor of Infectious Diseases at Imperial College London and a Clinical Infectious Diseases consultant at Hammersmith and St Mary’s Hospitals. She leads the Gram Positive Pathogenesis research group within the Department of Infectious Disease, where she is section head of Adult Infectious Diseases, and clinical director of Imperial’s new Centre for Bacteriology Resistance Biology. Her group works on the mechanisms that allow Streptococcus pyogenes to cause extreme clinical phenotypes in individuals and populations. The work ranges from pathogen molecular microbiology to host immune response and vaccines, working in collaboration with colleagues in the UK Health Security Agency. Shiranee trained in medicine at Cambridge and Barts, then specialised in Infectious Diseases in London where she obtained her PhD, and two postdoctoral research fellowships. She has held expert advisory roles in relation to sepsis, maternal sepsis, intravenous immunoglobulin, streptococcal vaccines, and outbreak prevention.